Technologies Available for License
Washington Research Foundation has an active licensing program that works on behalf of not-for-profit research institutions in Washington state.
Biotechnology
Expression of Polypeptides in Yeast
Using transformed strains of yeast, recombinant proteins may be produced inexpensively and in large quantities using our patented processes and compositions. Recombinant proteins are commonly used in drugs and vaccines, diagnostics, foodstuffs such as sweeteners and growth enhancers, industrial processes and for drug discovery. Licenses are available for research use only and for commercialization of recombinant proteins by field of use.
DNA Sequences for Human Alpha-1-Antitrypsin
The
cDNA, and nucleic acids complementary to the cDNA, encoding human
Alpha-1-Antitrypsin (AAT), a protease inhibitor, are claimed in our patents.
Licenses to produce a recombinant AAT protein therapeutic or an AAT gene therapy
are available.
Gene Sequences of the Chlamydia trachomatis Major Outer
Membrane Protein (MOMP)
Chlamydia trachomatis causes a common sexually transmitted disease as
well as trachoma, the world's leading cause of blindness. Researchers at
the University of Washington in collaboration with Chiron cloned and expressed
the major outer membrane protein (MOMP) of C. trachomatis. Our
patents claim the use of the MOMP protein or nucleic acid sequences in vaccines
and diagnostics.
DNA Libraries
A patented method for producing a
single chromosome amplification library comprising flow-sorting chromosomes or
fragments of chromosomes and amplifying them for use in "in situ"
hybridization.
Diagnostics
Assays for Chondrogenesis
The patents claim immunoassays and nucleic acid-based assays for osteoarthritis, a degenerative disease of the articulating cartilage of joints. The technology is based upon detection of type IIA procollagen protein and mRNA.
Diagnostic Methods for Chlamydia pneumoniae (TWAR)
University of Washington researchers were the first to identify Chlamydia pneumoniae (or TWAR) as a pathogenic organism separate from C. trachomatis and C. psittaci and were the first to develop diagnostic methods for the detection of C. pneumoniae. The patented methods and compositions for direct and indirect organism detection using immunoassays are available for non-exclusive licensing.
Gene Sequences of the Chlamydia trachomatis Major Outer Membrane Protein (MOMP)
Chlamydia trachomatis causes a common sexually transmitted disease as well as trachoma, the world's leading cause of blindness. Researchers at the University of Washington in collaboration with Chiron cloned and expressed the major outer membrane protein (MOMP) of C. trachomatis. Our patents claim the use of the MOMP protein or nucleic acid sequences in vaccines and diagnostics.
Medical Devices
The Caroline Guide
The Caroline Guide is a simple non-invasive medical device that assists a surgeon in the placement of posterior shunts for the treatment of hydrocephalus.
Translumenal Ultrasound Probe for 3D Imaging
A
patented multi-planar translumenal ultrasound probe that uses an
electro-magnetic sensor.
Vaccine Adjuvants
Use of Interleukin 7 to Improve Vaccine Potency
A patented method for improving the potency of a human or animal vaccine based on administering IL-7 to enhance humoral (antibody-based) immunity.
Electronics
Simplified High Frequency Broadband TunerBy combining direct conversion to baseband with novel tuning and signal processing schemes, this invention achieves advantages such as: elimination of the intermediate signals and attendant processing; simplification of processing the near direct current signal due to the use of a novel digital signal processing (DSP) technique; a wider tuning range than is available in superheterodyne receivers; use of the novel signal processing scheme allows the use of inexpensive and readily made bandpass filters; design requirements for the phase locked loop (PLL) are simplified due to a novel tuning technique which is made possible by the novel signal processing scheme; no adjustable or high- precision tuning circuits are required.